Major Opponents
- 111 Teams
| Record | Totals | Per Game | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 1 | Akron | 2008 | 2010 | 3 | 2 | 1 | 0 | .667 | 85 | 59 | 26 | 28.3 | 19.7 | 8.7 |
| 2 | Alabama | 1923 | 1952 | 2 | 1 | 1 | 0 | .500 | 29 | 61 | -32 | 14.5 | 30.5 | -16.0 |
| 3 | Amherst | 1900 | 1902 | 3 | 3 | 0 | 0 | 1.000 | 48 | 17 | 31 | 16.0 | 5.7 | 10.3 |
| 4 | Arizona | 1969 | 1990 | 2 | 2 | 0 | 0 | 1.000 | 51 | 0 | 51 | 25.5 | 0.0 | 25.5 |
| 5 | Army | 1899 | 2023 | 21 | 12 | 9 | 0 | .571 | 324 | 322 | 2 | 15.4 | 15.3 | 0.1 |
| 6 | Auburn | 1987 | 2002 | 3 | 1 | 1 | 1 | .500 | 81 | 67 | 14 | 27.0 | 22.3 | 4.7 |
| 7 | Ball State | 1993 | 1993 | 1 | 1 | 0 | 0 | 1.000 | 35 | 12 | 23 | 35.0 | 12.0 | 23.0 |
| 8 | Baylor | 1966 | 1967 | 2 | 1 | 1 | 0 | .500 | 19 | 35 | -16 | 9.5 | 17.5 | -8.0 |
| 9 | Boston College | 1944 | 2025 | 58 | 33 | 25 | 0 | .569 | 1370 | 1230 | 140 | 23.6 | 21.2 | 2.4 |
| 10 | Boston University | 1923 | 1960 | 14 | 10 | 3 | 1 | .750 | 381 | 193 | 188 | 27.2 | 13.8 | 13.4 |
| 11 | Bowling Green | 1973 | 1976 | 2 | 0 | 2 | 0 | .000 | 21 | 63 | -42 | 10.5 | 31.5 | -21.0 |
| 12 | Brigham Young | 2000 | 2002 | 2 | 1 | 1 | 0 | .500 | 63 | 56 | 7 | 31.5 | 28.0 | 3.5 |
| 13 | Brown | 1900 | 1935 | 14 | 9 | 2 | 3 | .750 | 213 | 59 | 154 | 15.2 | 4.2 | 11.0 |
| 14 | Bucknell | 1907 | 1919 | 4 | 4 | 0 | 0 | 1.000 | 77 | 6 | 71 | 19.3 | 1.5 | 17.8 |
| 15 | Buffalo | 2000 | 2007 | 4 | 4 | 0 | 0 | 1.000 | 151 | 36 | 115 | 37.8 | 9.0 | 28.8 |
| 16 | California | 1967 | 2024 | 3 | 2 | 1 | 0 | .667 | 53 | 82 | -29 | 17.7 | 27.3 | -9.7 |
| 17 | Carlisle | 1906 | 1914 | 9 | 3 | 6 | 0 | .333 | 98 | 131 | -33 | 10.9 | 14.6 | -3.7 |
| 18 | Central Florida | 2001 | 2003 | 3 | 3 | 0 | 0 | 1.000 | 97 | 59 | 38 | 32.3 | 19.7 | 12.7 |
| 19 | Central Michigan | 1999 | 2017 | 4 | 4 | 0 | 0 | 1.000 | 158 | 54 | 104 | 39.5 | 13.5 | 26.0 |
| 20 | Cincinnati | 1993 | 2012 | 13 | 5 | 8 | 0 | .385 | 285 | 301 | -16 | 21.9 | 23.2 | -1.2 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 21 | Clemson | 1995 | 2025 | 13 | 3 | 10 | 0 | .231 | 248 | 391 | -143 | 19.1 | 30.1 | -11.0 |
| 22 | Colgate | 1905 | 1981 | 54 | 25 | 25 | 4 | .500 | 864 | 614 | 250 | 16.0 | 11.4 | 4.6 |
| 23 | Colorado | 1992 | 1992 | 1 | 1 | 0 | 0 | 1.000 | 26 | 22 | 4 | 26.0 | 22.0 | 4.0 |
| 24 | Columbia | 1901 | 1948 | 23 | 10 | 9 | 4 | .522 | 202 | 295 | -93 | 8.8 | 12.8 | -4.0 |
| 25 | Connecticut | 2004 | 2025 | 14 | 8 | 6 | 0 | .571 | 376 | 359 | 17 | 26.9 | 25.6 | 1.2 |
| 26 | Cornell | 1899 | 1958 | 25 | 11 | 14 | 0 | .440 | 341 | 377 | -36 | 13.6 | 15.1 | -1.4 |
| 27 | Dartmouth | 1914 | 1951 | 10 | 3 | 6 | 1 | .350 | 89 | 138 | -49 | 8.9 | 13.8 | -4.9 |
| 28 | Dickinson | 1899 | 1900 | 2 | 2 | 0 | 0 | 1.000 | 24 | 7 | 17 | 12.0 | 3.5 | 8.5 |
| 29 | Duke | 1938 | 2025 | 6 | 1 | 5 | 0 | .167 | 92 | 163 | -71 | 15.3 | 27.2 | -11.8 |
| 30 | East Carolina | 1988 | 2001 | 10 | 7 | 3 | 0 | .700 | 321 | 205 | 116 | 32.1 | 20.5 | 11.6 |
| 31 | Eastern Michigan | 1995 | 1995 | 1 | 1 | 0 | 0 | 1.000 | 52 | 24 | 28 | 52.0 | 24.0 | 28.0 |
| 32 | Florida | 1931 | 1998 | 4 | 2 | 2 | 0 | .500 | 81 | 80 | 1 | 20.3 | 20.0 | 0.3 |
| 33 | Florida State | 1966 | 2023 | 16 | 2 | 14 | 0 | .125 | 253 | 559 | -306 | 15.8 | 34.9 | -19.1 |
| 34 | Fordham | 1909 | 1954 | 7 | 4 | 2 | 1 | .643 | 131 | 118 | 13 | 18.7 | 16.9 | 1.9 |
| 35 | George Washington | 1962 | 1962 | 1 | 1 | 0 | 0 | 1.000 | 35 | 0 | 35 | 35.0 | 0.0 | 35.0 |
| 36 | Georgetown | 1927 | 1940 | 3 | 1 | 1 | 1 | .500 | 38 | 47 | -9 | 12.7 | 15.7 | -3.0 |
| 37 | Georgia | 1989 | 1989 | 1 | 1 | 0 | 0 | 1.000 | 19 | 18 | 1 | 19.0 | 18.0 | 1.0 |
| 38 | Georgia Tech | 2001 | 2025 | 7 | 2 | 5 | 0 | .286 | 127 | 240 | -113 | 18.1 | 34.3 | -16.1 |
| 39 | Hamilton | 1907 | 1907 | 1 | 1 | 0 | 0 | 1.000 | 22 | 0 | 22 | 22.0 | 0.0 | 22.0 |
| 40 | Holy Cross | 1905 | 1973 | 27 | 23 | 4 | 0 | .852 | 756 | 306 | 450 | 28.0 | 11.3 | 16.7 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 41 | Houston | 1970 | 1996 | 2 | 1 | 1 | 0 | .500 | 45 | 59 | -14 | 22.5 | 29.5 | -7.0 |
| 42 | Illinois | 1909 | 2007 | 12 | 2 | 10 | 0 | .167 | 166 | 316 | -150 | 13.8 | 26.3 | -12.5 |
| 43 | Indiana | 1919 | 1982 | 7 | 3 | 4 | 0 | .429 | 67 | 55 | 12 | 9.6 | 7.9 | 1.7 |
| 44 | Iowa | 1975 | 2007 | 4 | 1 | 3 | 0 | .250 | 26 | 103 | -77 | 6.5 | 25.8 | -19.3 |
| 45 | Iowa State | 1957 | 1969 | 2 | 1 | 0 | 1 | .750 | 21 | 20 | 1 | 10.5 | 10.0 | 0.5 |
| 46 | Kansas | 1959 | 1980 | 8 | 4 | 4 | 0 | .500 | 154 | 138 | 16 | 19.3 | 17.3 | 2.0 |
| 47 | Kansas State | 1997 | 2010 | 3 | 2 | 1 | 0 | .667 | 80 | 72 | 8 | 26.7 | 24.0 | 2.7 |
| 48 | Kent State | 1974 | 1985 | 3 | 2 | 1 | 0 | .667 | 70 | 30 | 40 | 23.3 | 10.0 | 13.3 |
| 49 | Kentucky | 1999 | 1999 | 1 | 1 | 0 | 0 | 1.000 | 20 | 13 | 7 | 20.0 | 13.0 | 7.0 |
| 50 | Lafayette | 1901 | 1912 | 5 | 2 | 2 | 1 | .500 | 46 | 30 | 16 | 9.2 | 6.0 | 3.2 |
| 51 | Lehigh | 1905 | 1905 | 1 | 1 | 0 | 0 | 1.000 | 17 | 0 | 17 | 17.0 | 0.0 | 17.0 |
| 52 | Liberty | 2019 | 2021 | 3 | 2 | 1 | 0 | .667 | 69 | 59 | 10 | 23.0 | 19.7 | 3.3 |
| 53 | Louisiana State | 1964 | 2017 | 4 | 1 | 3 | 0 | .250 | 83 | 92 | -9 | 20.8 | 23.0 | -2.3 |
| 54 | Louisville | 1985 | 2022 | 21 | 8 | 13 | 0 | .381 | 470 | 612 | -142 | 22.4 | 29.1 | -6.8 |
| 55 | Maryland | 1920 | 2019 | 37 | 19 | 16 | 2 | .541 | 657 | 645 | 12 | 17.8 | 17.4 | 0.3 |
| 56 | McNeese State | 1979 | 1979 | 1 | 1 | 0 | 0 | 1.000 | 31 | 7 | 24 | 31.0 | 7.0 | 24.0 |
| 57 | Mercer | 1924 | 1924 | 1 | 1 | 0 | 0 | 1.000 | 26 | 0 | 26 | 26.0 | 0.0 | 26.0 |
| 58 | Miami (FL) | 1960 | 2025 | 25 | 8 | 17 | 0 | .320 | 448 | 675 | -227 | 17.9 | 27.0 | -9.1 |
| 59 | Miami (OH) | 1980 | 2007 | 4 | 3 | 1 | 0 | .750 | 108 | 65 | 43 | 27.0 | 16.3 | 10.8 |
| 60 | Michigan | 1908 | 1999 | 12 | 5 | 6 | 1 | .458 | 157 | 203 | -46 | 13.1 | 16.9 | -3.8 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 61 | Michigan State | 1931 | 1990 | 12 | 2 | 9 | 1 | .208 | 125 | 264 | -139 | 10.4 | 22.0 | -11.6 |
| 62 | Middle Tennessee State | 2017 | 2017 | 1 | 0 | 1 | 0 | .000 | 23 | 30 | -7 | 23.0 | 30.0 | -7.0 |
| 63 | Minnesota | 1995 | 2022 | 6 | 2 | 4 | 0 | .333 | 131 | 137 | -6 | 21.8 | 22.8 | -1.0 |
| 64 | Mississippi State | 1985 | 1986 | 2 | 0 | 2 | 0 | .000 | 20 | 54 | -34 | 10.0 | 27.0 | -17.0 |
| 65 | Missouri | 1986 | 2012 | 3 | 3 | 0 | 0 | 1.000 | 96 | 49 | 47 | 32.0 | 16.3 | 15.7 |
| 66 | Navy | 1959 | 1989 | 27 | 19 | 8 | 0 | .704 | 653 | 396 | 257 | 24.2 | 14.7 | 9.5 |
| 67 | Nebraska | 1917 | 1984 | 12 | 7 | 5 | 0 | .583 | 154 | 146 | 8 | 12.8 | 12.2 | 0.7 |
| 68 | Nevada-Las Vegas | 2024 | 2024 | 1 | 1 | 0 | 0 | 1.000 | 44 | 41 | 3 | 44.0 | 41.0 | 3.0 |
| 69 | New York University | 1940 | 1941 | 2 | 2 | 0 | 0 | 1.000 | 78 | 13 | 65 | 39.0 | 6.5 | 32.5 |
| 70 | North Carolina | 1995 | 2025 | 8 | 3 | 5 | 0 | .375 | 164 | 248 | -84 | 20.5 | 31.0 | -10.5 |
| 71 | North Carolina Pre-Flight | 1942 | 1942 | 1 | 0 | 1 | 0 | .000 | 0 | 9 | -9 | 0.0 | 9.0 | -9.0 |
| 72 | North Carolina State | 1972 | 2024 | 17 | 4 | 13 | 0 | .235 | 379 | 510 | -131 | 22.3 | 30.0 | -7.7 |
| 73 | Northwestern | 1940 | 2013 | 11 | 5 | 6 | 0 | .455 | 265 | 308 | -43 | 24.1 | 28.0 | -3.9 |
| 74 | Notre Dame | 1914 | 2025 | 12 | 3 | 9 | 0 | .250 | 204 | 386 | -182 | 17.0 | 32.2 | -15.2 |
| 75 | Ohio | 2021 | 2024 | 2 | 2 | 0 | 0 | 1.000 | 67 | 31 | 36 | 33.5 | 15.5 | 18.0 |
| 76 | Ohio State | 1979 | 1992 | 5 | 1 | 4 | 0 | .200 | 74 | 140 | -66 | 14.8 | 28.0 | -13.2 |
| 77 | Oklahoma | 1958 | 1997 | 4 | 0 | 4 | 0 | .000 | 72 | 94 | -22 | 18.0 | 23.5 | -5.5 |
| 78 | Oregon State | 1961 | 1977 | 7 | 4 | 3 | 0 | .571 | 131 | 102 | 29 | 18.7 | 14.6 | 4.1 |
| 79 | Penn State | 1922 | 2013 | 71 | 23 | 43 | 5 | .359 | 836 | 1367 | -531 | 11.8 | 19.3 | -7.5 |
| 80 | Pittsburgh | 1916 | 2025 | 81 | 33 | 45 | 3 | .426 | 1607 | 1730 | -123 | 19.8 | 21.4 | -1.5 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 81 | Princeton | 1900 | 1915 | 6 | 0 | 5 | 1 | .083 | 7 | 133 | -126 | 1.2 | 22.2 | -21.0 |
| 82 | Purdue | 2004 | 2023 | 3 | 2 | 1 | 0 | .667 | 67 | 100 | -33 | 22.3 | 33.3 | -11.0 |
| 83 | Richmond | 1963 | 1963 | 1 | 1 | 0 | 0 | 1.000 | 50 | 0 | 50 | 50.0 | 0.0 | 50.0 |
| 84 | Rutgers | 1914 | 2021 | 41 | 27 | 13 | 1 | .671 | 1058 | 703 | 355 | 25.8 | 17.1 | 8.7 |
| 85 | South Florida | 2005 | 2023 | 11 | 2 | 9 | 0 | .182 | 164 | 391 | -227 | 14.9 | 35.5 | -20.6 |
| 86 | Southern California | 1924 | 2012 | 4 | 0 | 4 | 0 | .000 | 62 | 130 | -68 | 15.5 | 32.5 | -17.0 |
| 87 | Southern Methodist | 1932 | 2025 | 2 | 0 | 2 | 0 | .000 | 24 | 47 | -23 | 12.0 | 23.5 | -11.5 |
| 88 | Stanford | 2024 | 2024 | 1 | 0 | 1 | 0 | .000 | 24 | 26 | -2 | 24.0 | 26.0 | -2.0 |
| 89 | TCU | 1956 | 1956 | 1 | 0 | 1 | 0 | .000 | 27 | 28 | -1 | 27.0 | 28.0 | -1.0 |
| 90 | Temple | 1944 | 2012 | 36 | 25 | 10 | 1 | .708 | 969 | 525 | 444 | 26.9 | 14.6 | 12.3 |
| 91 | Tennessee | 1966 | 2025 | 4 | 0 | 4 | 0 | .000 | 80 | 130 | -50 | 20.0 | 32.5 | -12.5 |
| 92 | Texas | 1959 | 1993 | 3 | 2 | 0 | 1 | .833 | 75 | 56 | 19 | 25.0 | 18.7 | 6.3 |
| 93 | Toledo | 1999 | 2011 | 3 | 3 | 0 | 0 | 1.000 | 102 | 49 | 53 | 34.0 | 16.3 | 17.7 |
| 94 | Tulane | 1975 | 2013 | 9 | 8 | 1 | 0 | .889 | 279 | 133 | 146 | 31.0 | 14.8 | 16.2 |
| 95 | UCLA | 1959 | 1968 | 8 | 6 | 2 | 0 | .750 | 194 | 98 | 96 | 24.3 | 12.3 | 12.0 |
| 96 | Vanderbilt | 1990 | 1991 | 2 | 2 | 0 | 0 | 1.000 | 86 | 24 | 62 | 43.0 | 12.0 | 31.0 |
| 97 | Vermont | 1901 | 1901 | 1 | 1 | 0 | 0 | 1.000 | 38 | 0 | 38 | 38.0 | 0.0 | 38.0 |
| 98 | Villanova | 1953 | 1975 | 3 | 2 | 1 | 0 | .667 | 65 | 37 | 28 | 21.7 | 12.3 | 9.3 |
| 99 | Virginia | 1975 | 2022 | 6 | 3 | 3 | 0 | .500 | 137 | 125 | 12 | 22.8 | 20.8 | 2.0 |
| 100 | Virginia Tech | 1964 | 2024 | 21 | 12 | 9 | 0 | .571 | 504 | 582 | -78 | 24.0 | 27.7 | -3.7 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 101 | Wake Forest | 2006 | 2023 | 13 | 7 | 6 | 0 | .538 | 372 | 373 | -1 | 28.6 | 28.7 | -0.1 |
| 102 | Washington | 1973 | 2010 | 4 | 1 | 3 | 0 | .250 | 61 | 124 | -63 | 15.3 | 31.0 | -15.8 |
| 103 | Washington & Jefferson | 1919 | 1921 | 3 | 1 | 2 | 0 | .333 | 24 | 30 | -6 | 8.0 | 10.0 | -2.0 |
| 104 | Washington State | 1979 | 2024 | 2 | 2 | 0 | 0 | 1.000 | 104 | 60 | 44 | 52.0 | 30.0 | 22.0 |
| 105 | West Virginia | 1945 | 2018 | 61 | 34 | 27 | 0 | .557 | 1260 | 1184 | 76 | 20.7 | 19.4 | 1.2 |
| 106 | Western Michigan | 2018 | 2023 | 3 | 3 | 0 | 0 | 1.000 | 155 | 82 | 73 | 51.7 | 27.3 | 24.3 |
| 107 | William & Mary | 1923 | 1968 | 4 | 4 | 0 | 0 | 1.000 | 149 | 10 | 139 | 37.3 | 2.5 | 34.8 |
| 108 | Williams | 1899 | 1902 | 2 | 1 | 1 | 0 | .500 | 26 | 23 | 3 | 13.0 | 11.5 | 1.5 |
| 109 | Wisconsin | 1941 | 1997 | 5 | 3 | 1 | 1 | .700 | 131 | 78 | 53 | 26.2 | 15.6 | 10.6 |
| 110 | Wyoming | 2006 | 2006 | 1 | 1 | 0 | 0 | 1.000 | 40 | 34 | 6 | 40.0 | 34.0 | 6.0 |
| 111 | Yale | 1902 | 1912 | 9 | 0 | 9 | 0 | .000 | 6 | 167 | -161 | 0.7 | 18.6 | -17.9 |


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