12 Games
| G | Date | Day | School | Opponent | Conf | Pts | Opp | W | L | Streak | Notes | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sep 1, 2005 | Thu | Houston | Oregon | Pac-10 | L | 24 | 38 | 0 | 1 | L 1 | ||
| 2 | Sep 10, 2005 | Sat | Houston | Sam Houston | Non-Major | W | 31 | 10 | 1 | 1 | W 1 | ||
| 3 | Sep 16, 2005 | Fri | Houston | @ | UTEP | CUSA | L | 41 | 44 | 1 | 2 | L 1 | |
| 4 | Oct 1, 2005 | Sat | Houston | @ | Tulsa | CUSA | W | 30 | 23 | 2 | 2 | W 1 | |
| 5 | Oct 8, 2005 | Sat | Houston | N | Tulane | CUSA | W | 35 | 14 | 3 | 2 | W 2 | |
| 6 | Oct 15, 2005 | Sat | Houston | Memphis | CUSA | L | 20 | 35 | 3 | 3 | L 1 | ||
| 7 | Oct 22, 2005 | Sat | Houston | @ | Mississippi State | SEC | W | 28 | 16 | 4 | 3 | W 1 | |
| 8 | Nov 5, 2005 | Sat | Houston | @ | UCF | CUSA | L | 29 | 31 | 4 | 4 | L 1 | |
| 9 | Nov 13, 2005 | Sun | Houston | Southern Mississippi | CUSA | W | 27 | 24 | 5 | 4 | W 1 | ||
| 10 | Nov 19, 2005 | Sat | Houston | SMU | CUSA | L | 24 | 29 | 5 | 5 | L 1 | ||
| 11 | Nov 26, 2005 | Sat | Houston | Rice | CUSA | W | 35 | 18 | 6 | 5 | W 1 | ||
| 12 | Dec 23, 2005 | Fri | Houston | N | Kansas | Big 12 | L | 13 | 42 | 6 | 6 | L 1 | Fort Worth Bowl (Fort Worth, TX) |
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