| Rk | Gcar | Gtm | Date | School | Opponent | Type | Result | Bowl | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 3 | 2 | 2021-09-11 | Wake Forest | Norfolk St. | REG (Non-Conf) | W 41-16 | ||
| 2 | 4 | 8 | 2021-10-30 | Wake Forest | Duke | REG (Conf) | W 45-7 | ||
| 3 | 5 | 9 | 2021-11-06 | Wake Forest | @ | North Carolina | REG (Non-Conf) | L 55-58 | |
| 4 | 6 | 10 | 2021-11-13 | Wake Forest | North Carolina State | REG (Conf) | W 45-42 | ||
| 5 | 7 | 11 | 2021-11-20 | Wake Forest | @ | Clemson | REG (Conf) | L 27-48 | |
| 6 | 8 | 12 | 2021-11-27 | Wake Forest | @ | Boston College | REG (Conf) | W 41-10 | |
| 7 | 9 | 13 | 2021-12-04 | Wake Forest | N | Pitt | Conf Championship | L 21-45 | |
| 8 | 10 | 14 | 2021-12-31 | Wake Forest | N | Rutgers | Bowl | W 38-10 | Gator Bowl |
| 5-3 |
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