13 Games
- Conference games only
| Rk | Date | Day | Winner | Pts | Loser | Pts | Notes | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oct 2, 1915 | Sat | Nebraska | 48 | Drake | 13 | ||
| Rk | Date | Day | Winner | Pts | Loser | Pts | Notes | |
| 2 | Oct 9, 1915 | Sat | Nebraska | 31 | Kansas State | 0 | ||
| 3 | Oct 9, 1915 | Sat | Washington (MO) | 13 | Missouri | 0 | ||
| Rk | Date | Day | Winner | Pts | Loser | Pts | Notes | |
| 4 | Oct 16, 1915 | Sat | Kansas | 30 | Drake | 7 | ||
| Rk | Date | Day | Winner | Pts | Loser | Pts | Notes | |
| 5 | Oct 23, 1915 | Sat | Iowa State | 14 | Missouri | 6 | ||
| 6 | Oct 23, 1915 | Sat | Kansas | 19 | @ | Kansas State | 7 | |
| Rk | Date | Day | Winner | Pts | Loser | Pts | Notes | |
| 7 | Oct 29, 1915 | Fri | Kansas State | 0 | @ | Missouri | 0 | |
| 8 | Oct 30, 1915 | Sat | Drake | 26 | Washington (MO) | 16 | ||
| 9 | Oct 30, 1915 | Sat | Nebraska | 21 | @ | Iowa State | 0 | |
| Rk | Date | Day | Winner | Pts | Loser | Pts | Notes | |
| 10 | Nov 13, 1915 | Sat | Missouri | 41 | Drake | 13 | ||
| 11 | Nov 13, 1915 | Sat | Nebraska | 33 | @ | Kansas | 0 | |
| Rk | Date | Day | Winner | Pts | Loser | Pts | Notes | |
| 12 | Nov 25, 1915 | Thu | Iowa State | 28 | @ | Drake | 14 | |
| 13 | Nov 25, 1915 | Thu | Kansas | 8 | @ | Missouri | 6 |
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