AP Poll Summary
| Pre | 9/7 | 9/13 | 9/19 | 9/26 | 10/3 | 10/10 | 10/17 | 10/24 | 10/31 | 11/7 | 11/14 | 11/21 | 11/28 | 12/5 | Final |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | 6 | 6 | 9 | 25 | 22 | 19 | 14 |
13 Games
| G | Date | Time | Day | School | Opponent | Conf | Pts | Opp | W | L | Streak | Notes | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sep 4, 2021 | 7:30 PM | Sat | (3) Clemson | N | (5) Georgia | SEC | L | 3 | 10 | 0 | 1 | L 1 | Bank of America Stadium - Charlotte, North Carolina |
| 2 | Sep 11, 2021 | 5:00 PM | Sat | (6) Clemson | South Carolina State | Non-Major | W | 49 | 3 | 1 | 1 | W 1 | ||
| 3 | Sep 18, 2021 | 3:30 PM | Sat | (6) Clemson | Georgia Tech | ACC | W | 14 | 8 | 2 | 1 | W 2 | ||
| 4 | Sep 25, 2021 | 3:30 PM | Sat | (9) Clemson | @ | North Carolina State | ACC | L | 21 | 27 | 2 | 2 | L 1 | |
| 5 | Oct 2, 2021 | 7:30 PM | Sat | (25) Clemson | Boston College | ACC | W | 19 | 13 | 3 | 2 | W 1 | ||
| 6 | Oct 15, 2021 | 7:00 PM | Fri | Clemson | @ | Syracuse | ACC | W | 17 | 14 | 4 | 2 | W 2 | |
| 7 | Oct 23, 2021 | 3:30 PM | Sat | Clemson | @ | (23) Pitt | ACC | L | 17 | 27 | 4 | 3 | L 1 | |
| 8 | Oct 30, 2021 | 3:30 PM | Sat | Clemson | Florida State | ACC | W | 30 | 20 | 5 | 3 | W 1 | ||
| 9 | Nov 6, 2021 | 7:30 PM | Sat | Clemson | @ | Louisville | ACC | W | 30 | 24 | 6 | 3 | W 2 | |
| 10 | Nov 13, 2021 | 12:00 PM | Sat | Clemson | Connecticut | Ind | W | 44 | 7 | 7 | 3 | W 3 | ||
| 11 | Nov 20, 2021 | 12:00 PM | Sat | Clemson | (13) Wake Forest | ACC | W | 48 | 27 | 8 | 3 | W 4 | ||
| 12 | Nov 27, 2021 | 7:30 PM | Sat | Clemson | @ | South Carolina | SEC | W | 30 | 0 | 9 | 3 | W 5 | |
| 13 | Dec 29, 2021 | 5:45 PM | Wed | (19) Clemson | N | Iowa State | Big 12 | W | 20 | 13 | 10 | 3 | W 6 | Cheez-It Bowl (Camping World Stadium - Orlando, Florida) |
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