Record: 81-62, .566 W-L% (3rd of 12) (Schedule and Results)
SRS: 6.42 (3rd of 12) ▪ SOS: 3.96 (2nd of 12)
Division Champions: Kansas State (North) and Oklahoma (South)
Conference Champion: Oklahoma (Won Championship Game 27-24)
Ranked in Preseason AP Poll: 5 (Colorado, Kansas State, Nebraska, Oklahoma and Texas)
Ranked in Final AP Poll: 5 (Iowa State, Kansas State, Nebraska, Oklahoma and Texas)
| Overall | Conference | Pts/G | SRS | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| North | W | L | Pct | W | L | Pct | Own | Opp | SRS | SOS | Notes |
| Nebraska | 10 | 2 | .833 | 6 | 2 | .750 | 43.5 | 19.2 | 19.01 | 4.51 | |
| Kansas State | 11 | 3 | .786 | 6 | 2 | .750 | 39.2 | 18.6 | 15.72 | 3.93 | |
| Iowa State | 9 | 3 | .750 | 5 | 3 | .625 | 28.6 | 26.8 | 6.43 | 2.84 | |
| Colorado | 3 | 8 | .273 | 3 | 5 | .375 | 22.9 | 25.8 | 3.56 | 7.92 | |
| Kansas | 4 | 7 | .364 | 2 | 6 | .250 | 23.7 | 32.6 | -1.95 | 4.60 | |
| Missouri | 3 | 8 | .273 | 2 | 6 | .250 | 23.2 | 31.6 | -2.63 | 3.55 | |
| South | W | L | Pct | W | L | Pct | Own | Opp | SRS | SOS | Notes |
| Oklahoma | 13 | 0 | 1.000 | 8 | 0 | 1.000 | 37.0 | 14.9 | 21.56 | 5.32 | |
| Texas | 9 | 3 | .750 | 7 | 1 | .875 | 37.9 | 19.3 | 13.78 | 0.78 | |
| Texas A&M | 7 | 5 | .583 | 5 | 3 | .625 | 29.0 | 19.9 | 11.44 | 5.03 | |
| Texas Tech | 7 | 6 | .538 | 3 | 5 | .375 | 25.4 | 21.4 | 4.81 | 1.65 | |
| Oklahoma State | 3 | 8 | .273 | 1 | 7 | .125 | 18.4 | 27.5 | -3.18 | 2.63 | |
| Baylor | 2 | 9 | .182 | 0 | 8 | .000 | 12.6 | 36.1 | -11.48 | 4.71 | |
| School | Pre | 8/27 | 9/3 | 9/10 | 9/17 | 9/24 | 10/1 | 10/8 | 10/15 | 10/22 | 10/29 | 11/5 | 11/12 | 11/19 | 11/26 | 12/3 | Final |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Oklahoma | 19 | 19 | 20 | 18 | 17 | 14 | 10 | 8 | 3 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Nebraska | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 5 | 4 | 10 | 9 | 10 | 9 | 8 |
| Kansas State | 8 | 8 | 7 | 7 | 4 | 5 | 4 | 2 | 10 | 10 | 19 | 16 | 9 | 8 | 8 | 11 | 9 |
| Texas | 7 | 7 | 6 | 5 | 15 | 13 | 11 | 25 | 22 | 20 | 19 | 14 | 12 | 12 | 12 | 12 | |
| Iowa State | 25 | ||||||||||||||||
| Colorado | 24 | 23 | |||||||||||||||
| Texas A&M | 25 | 24 | 23 | 21 | 22 |
| Date | Bowl | Winner/Tie | Pts | Loser/Tie | Pts | Notes |
|---|---|---|---|---|---|---|
| 2001-01-03 | Orange Bowl | Oklahoma | 13 | Florida State | 2 | Orange Bowl (Miami, FL) |
| 2001-01-01 | Cotton Bowl | Kansas State | 35 | Tennessee | 21 | Cotton Bowl (Dallas, TX) |
| 2000-12-31 | Independence Bowl | Mississippi State | 43 | Texas A&M | 41 | Independence Bowl (Shreveport, LA) |
| 2000-12-30 | Alamo Bowl | Nebraska | 66 | Northwestern | 17 | Alamo Bowl (San Antonio, TX) |
| 2000-12-29 | Holiday Bowl | Oregon | 35 | Texas | 30 | Holiday Bowl (San Diego, CA) |
| 2000-12-28 | Insight Bowl | Iowa State | 37 | Pittsburgh | 29 | Insight Bowl (Phoenix, AZ) |
| 2000-12-27 | Gallery Furniture Bowl | East Carolina | 40 | Texas Tech | 27 | Gallery Furniture Bowl (Houston, TX) |
| Big 12 Defensive Player of the Year: | Casey Hampton (Texas) |
| Big 12 Offensive Player of the Year: | Josh Heupel (Oklahoma) |
| Big 12 Coach of the Year: | Bob Stoops (Oklahoma) |