Record: 81-62, .566 W-L% (3rd of 12) (Schedule and Results)
SRS: 6.42 (3rd of 12) ▪ SOS: 3.96 (2nd of 12)
Division Champions: Kansas State (North) and Oklahoma (South)
Conference Champion: Oklahoma (Won Championship Game 27-24)
Ranked in Preseason AP Poll: 5 (Colorado, Kansas State, Nebraska, Oklahoma and Texas)
Ranked in Final AP Poll: 5 (Iowa State, Kansas State, Nebraska, Oklahoma and Texas)
| Passing | Rushing | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Player | School | Cmp | Att | Pct | Yds | Y/A | AY/A | TD | Int | Rate | Att | Yds | Avg | TD |
| 1 | Jonathan Beasley | Kansas State | 156 | 313 | 49.8 | 2636 | 8.4 | 8.1 | 17 | 10 | 132.1 | 149 | 499 | 3.3 | 17 |
| 2 | Josh Heupel | Oklahoma | 280 | 433 | 64.7 | 3392 | 7.8 | 7.3 | 20 | 14 | 139.2 | 70 | 144 | 2.1 | 7 |
| 3 | Major Applewhite | Texas | 152 | 279 | 54.5 | 2164 | 7.8 | 7.9 | 18 | 7 | 135.9 | 28 | -73 | -2.6 | 1 |
| 4 | Mark Farris | Texas A&M | 208 | 347 | 59.9 | 2551 | 7.4 | 6.8 | 10 | 9 | 126.0 | 60 | 116 | 1.9 | 2 |
| 5 | Craig Ochs | Colorado | 145 | 245 | 59.2 | 1778 | 7.3 | 6.5 | 7 | 7 | 123.9 | 62 | 106 | 1.7 | 4 |
| 6 | Sage Rosenfels | Iowa State | 171 | 332 | 51.5 | 2300 | 6.9 | 5.8 | 8 | 12 | 110.4 | 77 | 372 | 4.8 | 10 |
| 7 | Dylen Smith | Kansas | 140 | 306 | 45.8 | 1963 | 6.4 | 5.5 | 10 | 11 | 103.2 | 125 | 371 | 3.0 | 9 |
| 8 | Aso Pogi | Oklahoma State | 139 | 247 | 56.3 | 1550 | 6.3 | 4.8 | 6 | 11 | 108.1 | 85 | 159 | 1.9 | 6 |
| 9 | Darius Outlaw | Missouri | 105 | 225 | 46.7 | 1391 | 6.2 | 3.8 | 9 | 16 | 97.6 | 110 | 259 | 2.4 | 5 |
| 10 | Kliff Kingsbury | Texas Tech | 361 | 584 | 61.8 | 3412 | 5.8 | 5.3 | 21 | 17 | 116.9 | 78 | 19 | 0.2 | 2 |