Record: 92-62, .597 W-L% (3rd of 12) (Schedule and Results)
SRS: 6.25 (3rd of 12) ▪ SOS: 3.09 (3rd of 12)
Division Champions: Missouri (North), Nebraska (North), Oklahoma (South) and Oklahoma State (South)
Conference Champion: Oklahoma (Won Championship Game 23-20)
Ranked in Preseason AP Poll: 3 (Nebraska, Oklahoma and Texas)
Ranked in Final AP Poll: 5 (Missouri, Nebraska, Oklahoma, Oklahoma State and Texas A&M)
| Overall | Conference | Pts/G | SRS | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| North | W | L | Pct | W | L | Pct | Own | Opp | SRS | SOS | Notes |
| Missouri | 10 | 3 | .769 | 6 | 2 | .750 | 29.8 | 16.1 | 13.98 | 3.29 | |
| Nebraska | 10 | 4 | .714 | 6 | 2 | .750 | 30.9 | 17.4 | 12.85 | 2.42 | |
| Kansas State | 7 | 6 | .538 | 3 | 5 | .375 | 33.6 | 29.1 | 4.11 | 1.26 | |
| Iowa State | 5 | 7 | .417 | 3 | 5 | .375 | 21.7 | 28.8 | 0.43 | 4.27 | |
| Colorado | 5 | 7 | .417 | 2 | 6 | .250 | 24.2 | 30.8 | 0.75 | 4.33 | |
| Kansas | 3 | 9 | .250 | 1 | 7 | .125 | 17.1 | 34.4 | -8.61 | 2.47 | |
| South | W | L | Pct | W | L | Pct | Own | Opp | SRS | SOS | Notes |
| Oklahoma | 12 | 2 | .857 | 6 | 2 | .750 | 37.2 | 21.8 | 17.11 | 5.40 | |
| Oklahoma State | 11 | 2 | .846 | 6 | 2 | .750 | 44.2 | 26.4 | 16.62 | 2.39 | |
| Texas A&M | 9 | 4 | .692 | 6 | 2 | .750 | 31.2 | 21.9 | 11.39 | 4.85 | |
| Baylor | 7 | 6 | .538 | 4 | 4 | .500 | 31.2 | 30.5 | 1.62 | 1.93 | |
| Texas Tech | 8 | 5 | .615 | 3 | 5 | .375 | 33.1 | 30.9 | 3.06 | 1.83 | |
| Texas | 5 | 7 | .417 | 2 | 6 | .250 | 23.8 | 23.7 | 1.71 | 2.63 | |
| School | Pre | 9/5 | 9/12 | 9/19 | 9/26 | 10/3 | 10/10 | 10/17 | 10/24 | 10/31 | 11/7 | 11/14 | 11/21 | 11/28 | 12/5 | Final |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Oklahoma | 7 | 10 | 7 | 8 | 8 | 6 | 6 | 3 | 11 | 11 | 19 | 16 | 14 | 10 | 9 | 6 |
| Oklahoma State | 22 | 20 | 17 | 20 | 19 | 12 | 12 | 10 | 16 | 16 | 13 | |||||
| Missouri | 24 | 21 | 18 | 7 | 14 | 20 | 15 | 15 | 15 | 14 | 18 | |||||
| Texas A&M | 23 | 18 | 17 | 19 | 18 | 19 | ||||||||||
| Nebraska | 8 | 6 | 8 | 6 | 6 | 7 | 5 | 14 | 14 | 9 | 9 | 9 | 16 | 13 | 17 | 20 |
| Baylor | 25 | 22 | ||||||||||||||
| Texas | 5 | 5 | 6 | 7 | 21 | 22 |
| Date | Bowl | Winner/Tie | Pts | Loser/Tie | Pts | Notes |
|---|---|---|---|---|---|---|
| 2011-01-07 | Cotton Bowl | Louisiana State | 41 | Texas A&M | 24 | Cotton Bowl (Arlington, TX) |
| 2011-01-01 | Fiesta Bowl | Oklahoma | 48 | Connecticut | 20 | Fiesta Bowl (Glendale, AZ) |
| 2011-01-01 | Ticket City Bowl | Texas Tech | 45 | Northwestern | 38 | Ticket City Bowl (Dallas, TX) |
| 2010-12-30 | Holiday Bowl | Washington | 19 | Nebraska | 7 | Holiday Bowl (San Diego, CA) |
| 2010-12-30 | Pinstripe Bowl | Syracuse | 36 | Kansas State | 34 | Pinstripe Bowl (Bronx, NY) |
| 2010-12-29 | Alamo Bowl | Oklahoma State | 36 | Arizona | 10 | Alamo Bowl (San Antonio, TX) |
| 2010-12-29 | Texas Bowl | Illinois | 38 | Baylor | 14 | Texas Bowl (Houston, TX) |
| 2010-12-28 | Insight Bowl | Iowa | 27 | Missouri | 24 | Insight Bowl (Tempe, AZ) |
| Big 12 Defensive Player of the Year: | Prince Amukamara (Nebraska) |
| Big 12 Offensive Player of the Year: | Justin Blackmon (Oklahoma State) |
| Big 12 Coach of the Year: | Mike Gundy (Oklahoma State) |