Record: 28-22-1, .559 W-L% (2nd of 12) (Schedule and Results)
SRS: 8.50 (4th of 12) ▪ SOS: 6.28 (4th of 12)
Conference Champion: Southern California, UCLA and Washington
Ranked in Preseason AP Poll: 0
Ranked in Final AP Poll: 2 (Southern California and Washington)
| Rk | Date | Day | Winner/Tie | Pts | Loser/Tie | Pts | Notes | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oct 10, 1959 | Sat | Washington | 10 | Stanford | 0 | ||
| Rk | Date | Day | Winner/Tie | Pts | Loser/Tie | Pts | Notes | |
| 2 | Oct 17, 1959 | Sat | (7) Southern California | 22 | @ | (18) Washington | 15 | |
| 3 | Oct 17, 1959 | Sat | UCLA | 19 | California | 12 | ||
| Rk | Date | Day | Winner/Tie | Pts | Loser/Tie | Pts | Notes | |
| 4 | Oct 24, 1959 | Sat | (5) Southern California | 30 | Stanford | 28 | ||
| Rk | Date | Day | Winner/Tie | Pts | Loser/Tie | Pts | Notes | |
| 5 | Oct 31, 1959 | Sat | (6) Southern California | 14 | @ | California | 7 | |
| 6 | Oct 31, 1959 | Sat | (17) Washington | 23 | @ | UCLA | 7 | |
| Rk | Date | Day | Winner/Tie | Pts | Loser/Tie | Pts | Notes | |
| 7 | Nov 7, 1959 | Sat | UCLA | 55 | @ | Stanford | 13 | |
| Rk | Date | Day | Winner/Tie | Pts | Loser/Tie | Pts | Notes | |
| 8 | Nov 14, 1959 | Sat | (13) Washington | 20 | @ | California | 0 | |
| Rk | Date | Day | Winner/Tie | Pts | Loser/Tie | Pts | Notes | |
| 9 | Nov 21, 1959 | Sat | California | 20 | @ | Stanford | 17 | |
| 10 | Nov 21, 1959 | Sat | UCLA | 10 | @ | (4) Southern California | 3 |