14 Games
| G | Date | Time | Day | School | Opponent | Conf | Pts | Opp | W | L | Streak | Notes | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sep 3, 2022 | 6:00 PM | Sat | Ohio | Florida Atlantic | CUSA | W | 41 | 38 | 1 | 0 | W 1 | ||
| 2 | Sep 10, 2022 | 12:00 PM | Sat | Ohio | @ | Penn State | Big Ten | L | 10 | 46 | 1 | 1 | L 1 | |
| 3 | Sep 17, 2022 | 2:00 PM | Sat | Ohio | @ | Iowa State | Big 12 | L | 10 | 43 | 1 | 2 | L 2 | |
| 4 | Sep 24, 2022 | 2:00 PM | Sat | Ohio | Fordham | Non-Major | W | 59 | 52 | 2 | 2 | W 1 | ||
| 5 | Oct 1, 2022 | 3:30 PM | Sat | Ohio | @ | Kent State | MAC | L | 24 | 31 | 2 | 3 | L 1 | |
| 6 | Oct 8, 2022 | 2:00 PM | Sat | Ohio | Akron | MAC | W | 55 | 34 | 3 | 3 | W 1 | ||
| 7 | Oct 15, 2022 | 3:30 PM | Sat | Ohio | @ | Western Michigan | MAC | W | 33 | 14 | 4 | 3 | W 2 | |
| 8 | Oct 22, 2022 | 2:00 PM | Sat | Ohio | Northern Illinois | MAC | W | 24 | 17 | 5 | 3 | W 3 | ||
| 9 | Nov 1, 2022 | 7:30 PM | Tue | Ohio | Buffalo | MAC | W | 45 | 24 | 6 | 3 | W 4 | ||
| 10 | Nov 8, 2022 | 7:30 PM | Tue | Ohio | @ | Miami (OH) | MAC | W | 37 | 21 | 7 | 3 | W 5 | |
| 11 | Nov 15, 2022 | 7:00 PM | Tue | Ohio | @ | Ball State | MAC | W | 32 | 18 | 8 | 3 | W 6 | |
| 12 | Nov 22, 2022 | 7:00 PM | Tue | Ohio | Bowling Green | MAC | W | 38 | 14 | 9 | 3 | W 7 | ||
| 13 | Dec 3, 2022 | 12:00 PM | Sat | Ohio | N | Toledo | MAC | L | 7 | 17 | 9 | 4 | L 1 | MAC Championship Game |
| 14 | Dec 30, 2022 | 4:30 PM | Fri | Ohio | N | Wyoming | MWC | W | 30 | 27 | 10 | 4 | W 1 | Arizona Bowl |
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