Denise Spencer had the following podium finishes at major championships: 1st in the 1950 British Empire Games 4×110 yards Freestyle Relay (with Denise Norton, Judy-Joy Davies, and Marjorie McQuade). She also competed in the 1950 British Empire Games 110 yards Freestyle and finished fourth.
|1948 Summer||18||London||Swimming||Women's 100 metres Freestyle||Australia||AUS||3 h2 r1/3|
|1948 Summer||18||London||Swimming||Women's 400 metres Freestyle||Australia||AUS||6 h2 r2/3|
|1948 Summer||18||London||Swimming||Australia||Round One||Heat Two||3||1:10.0|