Location: Laramie, Wyoming ▪ Colors: Brown & Gold
Stadium: War Memorial Stadium (cap. 32,580)
Record*: 101 Years, 474-518-26, .478 W-L% (Major School)
*W-L-T adjusted to 475-517-26 by NCAA.
Conferences: MWC, WAC, Skyline, MSAC, RMC and Ind
Conference Champion: 14 Times
Bowls: 13 Bowls, 6-7, .462 W-L% (Major Bowls)
Ranked in AP Poll: 0 Times (Preseason), 4 Times (Final), 56 Weeks (Total)
| Record | Totals | Per Game | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 1 | Air Force | 1957 | 2012 | 51 | 21 | 27 | 3 | .441 | 955 | 1180 | -225 | 18.7 | 23.1 | -4.4 | Game-by-Game |
| 2 | Arizona | 1936 | 1977 | 22 | 10 | 12 | 0 | .455 | 381 | 417 | -36 | 17.3 | 19.0 | -1.6 | Game-by-Game |
| 3 | Arizona State | 1951 | 1977 | 15 | 6 | 9 | 0 | .400 | 225 | 404 | -179 | 15.0 | 26.9 | -11.9 | Game-by-Game |
| 4 | Arkansas State | 1979 | 1990 | 2 | 2 | 0 | 0 | 1.000 | 51 | 41 | 10 | 25.5 | 20.5 | 5.0 | Game-by-Game |
| 5 | Army | 1965 | 1965 | 1 | 0 | 1 | 0 | .000 | 0 | 13 | -13 | 0.0 | 13.0 | -13.0 | Game-by-Game |
| 6 | Auburn | 2000 | 2000 | 1 | 0 | 1 | 0 | .000 | 21 | 35 | -14 | 21.0 | 35.0 | -14.0 | Game-by-Game |
| 7 | Baylor | 1949 | 1986 | 4 | 1 | 3 | 0 | .250 | 66 | 102 | -36 | 16.5 | 25.5 | -9.0 | Game-by-Game |
| 8 | Boise State | 2002 | 2012 | 7 | 0 | 7 | 0 | .000 | 88 | 241 | -153 | 12.6 | 34.4 | -21.9 | Game-by-Game |
| 9 | Bowling Green State | 2008 | 2011 | 2 | 1 | 1 | 0 | .500 | 44 | 72 | -28 | 22.0 | 36.0 | -14.0 | Game-by-Game |
| 10 | Brigham Young | 1922 | 2010 | 77 | 30 | 44 | 3 | .409 | 1386 | 1707 | -321 | 18.0 | 22.2 | -4.2 | Game-by-Game |
| 11 | Cal State Fullerton | 1981 | 1988 | 4 | 3 | 1 | 0 | .750 | 120 | 57 | 63 | 30.0 | 14.3 | 15.8 | Game-by-Game |
| 12 | California | 1990 | 1990 | 1 | 0 | 1 | 0 | .000 | 15 | 17 | -2 | 15.0 | 17.0 | -2.0 | Game-by-Game |
| 13 | Central Michigan | 2000 | 2002 | 2 | 1 | 1 | 0 | .500 | 51 | 42 | 9 | 25.5 | 21.0 | 4.5 | Game-by-Game |
| 14 | Chicago | 1928 | 1928 | 1 | 0 | 1 | 0 | .000 | 0 | 47 | -47 | 0.0 | 47.0 | -47.0 | Game-by-Game |
| 15 | Colorado | 1905 | 2009 | 26 | 2 | 23 | 1 | .096 | 155 | 704 | -549 | 6.0 | 27.1 | -21.1 | Game-by-Game |
| 16 | Colorado College | 1909 | 1937 | 16 | 0 | 15 | 1 | .031 | 86 | 402 | -316 | 5.4 | 25.1 | -19.8 | Game-by-Game |
| 17 | Colorado Mines | 1905 | 1936 | 19 | 7 | 12 | 0 | .368 | 186 | 345 | -159 | 9.8 | 18.2 | -8.4 | Game-by-Game |
| 18 | Colorado State | 1905 | 2012 | 98 | 44 | 50 | 4 | .469 | 1667 | 1807 | -140 | 17.0 | 18.4 | -1.4 | Game-by-Game |
| 19 | Creighton | 1927 | 1932 | 3 | 0 | 3 | 0 | .000 | 0 | 50 | -50 | 0.0 | 16.7 | -16.7 | Game-by-Game |
| 20 | Denver | 1909 | 1960 | 44 | 11 | 31 | 2 | .273 | 446 | 732 | -286 | 10.1 | 16.6 | -6.5 | Game-by-Game |
| Record | Totals | Per Game | |||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 21 | Florida | 1951 | 2005 | 2 | 0 | 2 | 0 | .000 | 14 | 45 | -31 | 7.0 | 22.5 | -15.5 | Game-by-Game |
| 22 | Florida Atlantic | 2009 | 2009 | 1 | 1 | 0 | 0 | 1.000 | 30 | 28 | 2 | 30.0 | 28.0 | 2.0 | Game-by-Game |
| 23 | Florida State | 1966 | 1966 | 1 | 1 | 0 | 0 | 1.000 | 28 | 20 | 8 | 28.0 | 20.0 | 8.0 | Game-by-Game |
| 24 | Fresno State | 1992 | 2012 | 8 | 4 | 4 | 0 | .500 | 223 | 233 | -10 | 27.9 | 29.1 | -1.3 | Game-by-Game |
| 25 | Georgia | 1998 | 1998 | 1 | 0 | 1 | 0 | .000 | 9 | 16 | -7 | 9.0 | 16.0 | -7.0 | Game-by-Game |
| 26 | Gonzaga | 1922 | 1922 | 1 | 0 | 1 | 0 | .000 | 0 | 77 | -77 | 0.0 | 77.0 | -77.0 | Game-by-Game |
| 27 | Hardin-Simmons | 1958 | 1958 | 1 | 1 | 0 | 0 | 1.000 | 14 | 6 | 8 | 14.0 | 6.0 | 8.0 | Game-by-Game |
| 28 | Hawaii | 1978 | 1997 | 20 | 12 | 8 | 0 | .600 | 559 | 390 | 169 | 28.0 | 19.5 | 8.5 | Game-by-Game |
| 29 | Houston | 1952 | 1988 | 7 | 1 | 6 | 0 | .143 | 75 | 219 | -144 | 10.7 | 31.3 | -20.6 | Game-by-Game |
| 30 | Idaho | 1921 | 2012 | 6 | 5 | 1 | 0 | .833 | 153 | 126 | 27 | 25.5 | 21.0 | 4.5 | Game-by-Game |
| 31 | Iowa | 1953 | 1987 | 2 | 0 | 2 | 0 | .000 | 26 | 41 | -15 | 13.0 | 20.5 | -7.5 | Game-by-Game |
| 32 | Iowa State | 1986 | 1997 | 4 | 3 | 1 | 0 | .750 | 141 | 86 | 55 | 35.3 | 21.5 | 13.8 | Game-by-Game |
| 33 | Kansas | 1961 | 2003 | 6 | 1 | 4 | 1 | .250 | 107 | 166 | -59 | 17.8 | 27.7 | -9.8 | Game-by-Game |
| 34 | Kansas State | 1952 | 1993 | 8 | 4 | 4 | 0 | .500 | 166 | 166 | 0 | 20.8 | 20.8 | 0.0 | Game-by-Game |
| 35 | Long Beach State | 1982 | 1982 | 1 | 1 | 0 | 0 | 1.000 | 36 | 27 | 9 | 36.0 | 27.0 | 9.0 | Game-by-Game |
| 36 | Louisiana State | 1967 | 1978 | 3 | 0 | 3 | 0 | .000 | 37 | 110 | -73 | 12.3 | 36.7 | -24.3 | Game-by-Game |
| 37 | Louisiana Tech | 1988 | 1998 | 2 | 2 | 0 | 0 | 1.000 | 69 | 25 | 44 | 34.5 | 12.5 | 22.0 | Game-by-Game |
| 38 | Louisiana-Lafayette | 1991 | 1991 | 1 | 1 | 0 | 0 | 1.000 | 28 | 15 | 13 | 28.0 | 15.0 | 13.0 | Game-by-Game |
| 39 | Louisiana-Monroe | 1994 | 2005 | 4 | 4 | 0 | 0 | 1.000 | 135 | 44 | 91 | 33.8 | 11.0 | 22.8 | Game-by-Game |
| 40 | Louisville | 1988 | 1995 | 4 | 3 | 1 | 0 | .750 | 118 | 81 | 37 | 29.5 | 20.3 | 9.3 | Game-by-Game |
| Record | Totals | Per Game | |||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 41 | Michigan State | 1976 | 1977 | 2 | 0 | 2 | 0 | .000 | 26 | 55 | -29 | 13.0 | 27.5 | -14.5 | Game-by-Game |
| 42 | Minnesota | 1946 | 1946 | 1 | 0 | 1 | 0 | .000 | 0 | 46 | -46 | 0.0 | 46.0 | -46.0 | Game-by-Game |
| 43 | Mississippi | 2004 | 2005 | 2 | 2 | 0 | 0 | 1.000 | 61 | 46 | 15 | 30.5 | 23.0 | 7.5 | Game-by-Game |
| 44 | Montana | 1951 | 1962 | 11 | 11 | 0 | 0 | 1.000 | 299 | 47 | 252 | 27.2 | 4.3 | 22.9 | Game-by-Game |
| 45 | Montana State | 1924 | 1936 | 13 | 7 | 6 | 0 | .538 | 140 | 121 | 19 | 10.8 | 9.3 | 1.5 | Game-by-Game |
| 46 | Nebraska | 1934 | 2011 | 6 | 0 | 6 | 0 | .000 | 83 | 241 | -158 | 13.8 | 40.2 | -26.3 | Game-by-Game |
| 47 | Nevada | 1992 | 2012 | 4 | 2 | 2 | 0 | .500 | 115 | 106 | 9 | 28.8 | 26.5 | 2.3 | Game-by-Game |
| 48 | Nevada-Las Vegas | 1978 | 2012 | 21 | 11 | 10 | 0 | .524 | 641 | 611 | 30 | 30.5 | 29.1 | 1.4 | Game-by-Game |
| 49 | New Mexico | 1931 | 2012 | 64 | 33 | 31 | 0 | .516 | 1408 | 1229 | 179 | 22.0 | 19.2 | 2.8 | Game-by-Game |
| 50 | New Mexico State | 1953 | 1953 | 1 | 1 | 0 | 0 | 1.000 | 47 | 0 | 47 | 47.0 | 0.0 | 47.0 | Game-by-Game |
| 51 | North Carolina State | 1959 | 1961 | 2 | 2 | 0 | 0 | 1.000 | 41 | 14 | 27 | 20.5 | 7.0 | 13.5 | Game-by-Game |
| 52 | Northern Colorado | 1924 | 1937 | 12 | 5 | 5 | 2 | .500 | 138 | 119 | 19 | 11.5 | 9.9 | 1.6 | Game-by-Game |
| 53 | Northwestern | 1979 | 1979 | 1 | 0 | 1 | 0 | .000 | 22 | 27 | -5 | 22.0 | 27.0 | -5.0 | Game-by-Game |
| 54 | Ohio | 2007 | 2008 | 2 | 2 | 0 | 0 | 1.000 | 55 | 53 | 2 | 27.5 | 26.5 | 1.0 | Game-by-Game |
| 55 | Ohio State | 1997 | 1997 | 1 | 0 | 1 | 0 | .000 | 10 | 24 | -14 | 10.0 | 24.0 | -14.0 | Game-by-Game |
| 56 | Oklahoma | 1976 | 1981 | 2 | 0 | 2 | 0 | .000 | 27 | 78 | -51 | 13.5 | 39.0 | -25.5 | Game-by-Game |
| 57 | Oklahoma State | 1953 | 2003 | 8 | 1 | 7 | 0 | .125 | 145 | 270 | -125 | 18.1 | 33.8 | -15.6 | Game-by-Game |
| 58 | Oregon State | 1958 | 1994 | 5 | 2 | 3 | 0 | .400 | 119 | 122 | -3 | 23.8 | 24.4 | -0.6 | Game-by-Game |
| 59 | Pacific | 1973 | 1986 | 3 | 2 | 1 | 0 | .667 | 86 | 84 | 2 | 28.7 | 28.0 | 0.7 | Game-by-Game |
| 60 | Rice | 1998 | 1998 | 1 | 1 | 0 | 0 | 1.000 | 34 | 24 | 10 | 34.0 | 24.0 | 10.0 | Game-by-Game |
| Record | Totals | Per Game | |||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 61 | Richmond | 1979 | 1980 | 2 | 2 | 0 | 0 | 1.000 | 44 | 21 | 23 | 22.0 | 10.5 | 11.5 | Game-by-Game |
| 62 | Saint Louis | 1932 | 1939 | 2 | 0 | 2 | 0 | .000 | 12 | 59 | -47 | 6.0 | 29.5 | -23.5 | Game-by-Game |
| 63 | San Diego State | 1978 | 2012 | 34 | 18 | 16 | 0 | .529 | 954 | 895 | 59 | 28.1 | 26.3 | 1.7 | Game-by-Game |
| 64 | San Francisco | 1946 | 1946 | 1 | 0 | 1 | 0 | .000 | 7 | 39 | -32 | 7.0 | 39.0 | -32.0 | Game-by-Game |
| 65 | San Jose State | 1959 | 1997 | 7 | 6 | 1 | 0 | .857 | 207 | 104 | 103 | 29.6 | 14.9 | 14.7 | Game-by-Game |
| 66 | Southern California | 1965 | 1965 | 1 | 0 | 1 | 0 | .000 | 6 | 56 | -50 | 6.0 | 56.0 | -50.0 | Game-by-Game |
| 67 | Southern Methodist | 1996 | 1998 | 3 | 2 | 1 | 0 | .667 | 88 | 46 | 42 | 29.3 | 15.3 | 14.0 | Game-by-Game |
| 68 | Syracuse | 2006 | 2006 | 1 | 0 | 1 | 0 | .000 | 34 | 40 | -6 | 34.0 | 40.0 | -6.0 | Game-by-Game |
| 69 | Temple | 1990 | 2011 | 2 | 1 | 1 | 0 | .500 | 53 | 60 | -7 | 26.5 | 30.0 | -3.5 | Game-by-Game |
| 70 | Tennessee | 1999 | 2008 | 3 | 1 | 2 | 0 | .333 | 37 | 96 | -59 | 12.3 | 32.0 | -19.7 | Game-by-Game |
| 71 | Texas | 1974 | 2012 | 5 | 0 | 5 | 0 | .000 | 44 | 163 | -119 | 8.8 | 32.6 | -23.8 | Game-by-Game |
| 72 | Texas A&M | 2000 | 2004 | 3 | 0 | 3 | 0 | .000 | 23 | 110 | -87 | 7.7 | 36.7 | -29.0 | Game-by-Game |
| 73 | Texas Christian | 1998 | 2011 | 8 | 2 | 6 | 0 | .250 | 112 | 277 | -165 | 14.0 | 34.6 | -20.6 | Game-by-Game |
| 74 | Texas Tech | 1938 | 1992 | 5 | 3 | 2 | 0 | .600 | 85 | 126 | -41 | 17.0 | 25.2 | -8.2 | Game-by-Game |
| 75 | Texas-El Paso | 1962 | 1995 | 33 | 26 | 6 | 1 | .803 | 979 | 536 | 443 | 29.7 | 16.2 | 13.4 | Game-by-Game |
| 76 | Toledo | 2010 | 2012 | 2 | 1 | 1 | 0 | .500 | 51 | 49 | 2 | 25.5 | 24.5 | 1.0 | Game-by-Game |
| 77 | Tulsa | 1954 | 1998 | 5 | 3 | 2 | 0 | .600 | 74 | 123 | -49 | 14.8 | 24.6 | -9.8 | Game-by-Game |
| 78 | UCLA | 2004 | 2004 | 1 | 1 | 0 | 0 | 1.000 | 24 | 21 | 3 | 24.0 | 21.0 | 3.0 | Game-by-Game |
| 79 | Utah | 1905 | 2010 | 81 | 31 | 49 | 1 | .389 | 1327 | 2116 | -789 | 16.4 | 26.1 | -9.7 | Game-by-Game |
| 80 | Utah State | 1912 | 2011 | 62 | 24 | 34 | 4 | .419 | 1041 | 1209 | -168 | 16.8 | 19.5 | -2.7 | Game-by-Game |
| Record | Totals | Per Game | |||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 81 | Virginia | 2006 | 2007 | 2 | 1 | 1 | 0 | .500 | 35 | 16 | 19 | 17.5 | 8.0 | 9.5 | Game-by-Game |
| 82 | Washington | 1979 | 2002 | 2 | 0 | 2 | 0 | .000 | 9 | 76 | -67 | 4.5 | 38.0 | -33.5 | Game-by-Game |
| 83 | Washington & Lee | 1950 | 1950 | 1 | 1 | 0 | 0 | 1.000 | 20 | 7 | 13 | 20.0 | 7.0 | 13.0 | Game-by-Game |
| 84 | Washington State | 1962 | 1990 | 5 | 2 | 3 | 0 | .400 | 128 | 113 | 15 | 25.6 | 22.6 | 3.0 | Game-by-Game |
| 85 | Western Michigan | 1996 | 1996 | 1 | 1 | 0 | 0 | 1.000 | 42 | 28 | 14 | 42.0 | 28.0 | 14.0 | Game-by-Game |
| 86 | Western State | 1925 | 1933 | 3 | 3 | 0 | 0 | 1.000 | 84 | 0 | 84 | 28.0 | 0.0 | 28.0 | Game-by-Game |
| 87 | Wichita State | 1966 | 1982 | 3 | 3 | 0 | 0 | 1.000 | 109 | 27 | 82 | 36.3 | 9.0 | 27.3 | Game-by-Game |
| 88 | Wisconsin | 1973 | 1986 | 3 | 1 | 2 | 0 | .333 | 66 | 90 | -24 | 22.0 | 30.0 | -8.0 | Game-by-Game |