Location: Columbus, Ohio ▪ Colors: Scarlet & Gray
Stadium: Ohio Stadium (cap. 102,329)
Record*: 101 Years, 729-249-36, .737 W-L% (Major School)
*W-L-T adjusted to 717-248-36 by NCAA.
Conferences: Big Ten, Western and Ind
Conference Champion: 35 Times
Bowls: 43 Bowls, 20-23, .465 W-L% (Major Bowls)
Ranked in AP Poll: 59 Times (Preseason), 52 Times (Final), 804 Weeks (Total)
| Record | Totals | Per Game | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 1 | Air Force | 1990 | 1990 | 1 | 0 | 1 | 0 | .000 | 11 | 23 | -12 | 11.0 | 23.0 | -12.0 | Game-by-Game |
| 2 | Akron | 2001 | 2011 | 3 | 3 | 0 | 0 | 1.000 | 90 | 16 | 74 | 30.0 | 5.3 | 24.7 | Game-by-Game |
| 3 | Alabama | 1977 | 1994 | 3 | 0 | 3 | 0 | .000 | 33 | 75 | -42 | 11.0 | 25.0 | -14.0 | Game-by-Game |
| 4 | Alabama-Birmingham | 2012 | 2012 | 1 | 1 | 0 | 0 | 1.000 | 29 | 15 | 14 | 29.0 | 15.0 | 14.0 | Game-by-Game |
| 5 | Arizona | 1967 | 2000 | 4 | 3 | 1 | 0 | .750 | 100 | 65 | 35 | 25.0 | 16.3 | 8.8 | Game-by-Game |
| 6 | Arizona State | 1980 | 1996 | 2 | 2 | 0 | 0 | 1.000 | 58 | 38 | 20 | 29.0 | 19.0 | 10.0 | Game-by-Game |
| 7 | Arkansas | 2010 | 2010 | 1 | 1 | 0 | 0 | 1.000 | 31 | 26 | 5 | 31.0 | 26.0 | 5.0 | Game-by-Game |
| 8 | Auburn | 1917 | 1989 | 2 | 0 | 1 | 1 | .250 | 14 | 31 | -17 | 7.0 | 15.5 | -8.5 | Game-by-Game |
| 9 | Baylor | 1978 | 1982 | 2 | 2 | 0 | 0 | 1.000 | 55 | 42 | 13 | 27.5 | 21.0 | 6.5 | Game-by-Game |
| 10 | Boston College | 1989 | 1995 | 3 | 3 | 0 | 0 | 1.000 | 103 | 45 | 58 | 34.3 | 15.0 | 19.3 | Game-by-Game |
| 11 | Bowling Green State | 1992 | 2006 | 4 | 4 | 0 | 0 | 1.000 | 120 | 43 | 77 | 30.0 | 10.8 | 19.3 | Game-by-Game |
| 12 | Brigham Young | 1982 | 1993 | 3 | 3 | 0 | 0 | 1.000 | 85 | 45 | 40 | 28.3 | 15.0 | 13.3 | Game-by-Game |
| 13 | California | 1920 | 2012 | 7 | 6 | 1 | 0 | .857 | 176 | 123 | 53 | 25.1 | 17.6 | 7.6 | Game-by-Game |
| 14 | Carlisle | 1904 | 1904 | 1 | 0 | 1 | 0 | .000 | 0 | 23 | -23 | 0.0 | 23.0 | -23.0 | Game-by-Game |
| 15 | Central Florida | 2012 | 2012 | 1 | 1 | 0 | 0 | 1.000 | 31 | 16 | 15 | 31.0 | 16.0 | 15.0 | Game-by-Game |
| 16 | Chicago | 1920 | 1939 | 14 | 10 | 2 | 2 | .786 | 302 | 70 | 232 | 21.6 | 5.0 | 16.6 | Game-by-Game |
| 17 | Cincinnati | 1999 | 2006 | 4 | 4 | 0 | 0 | 1.000 | 121 | 52 | 69 | 30.3 | 13.0 | 17.3 | Game-by-Game |
| 18 | Clemson | 1978 | 1978 | 1 | 0 | 1 | 0 | .000 | 15 | 17 | -2 | 15.0 | 17.0 | -2.0 | Game-by-Game |
| 19 | Colgate | 1923 | 1934 | 2 | 1 | 0 | 1 | .750 | 33 | 30 | 3 | 16.5 | 15.0 | 1.5 | Game-by-Game |
| 20 | Colorado | 1971 | 2011 | 5 | 4 | 1 | 0 | .800 | 127 | 70 | 57 | 25.4 | 14.0 | 11.4 | Game-by-Game |
| Record | Totals | Per Game | |||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 21 | Columbia | 1925 | 1926 | 2 | 2 | 0 | 0 | 1.000 | 41 | 7 | 34 | 20.5 | 3.5 | 17.0 | Game-by-Game |
| 22 | Cornell | 1939 | 1940 | 2 | 0 | 2 | 0 | .000 | 21 | 44 | -23 | 10.5 | 22.0 | -11.5 | Game-by-Game |
| 23 | Drake | 1935 | 1935 | 1 | 1 | 0 | 0 | 1.000 | 85 | 7 | 78 | 85.0 | 7.0 | 78.0 | Game-by-Game |
| 24 | Duke | 1955 | 1981 | 4 | 3 | 1 | 0 | .750 | 96 | 56 | 40 | 24.0 | 14.0 | 10.0 | Game-by-Game |
| 25 | Eastern Michigan | 2010 | 2010 | 1 | 1 | 0 | 0 | 1.000 | 73 | 20 | 53 | 73.0 | 20.0 | 53.0 | Game-by-Game |
| 26 | Florida | 2006 | 2011 | 2 | 0 | 2 | 0 | .000 | 31 | 65 | -34 | 15.5 | 32.5 | -17.0 | Game-by-Game |
| 27 | Florida State | 1981 | 1997 | 3 | 0 | 3 | 0 | .000 | 58 | 101 | -43 | 19.3 | 33.7 | -14.3 | Game-by-Game |
| 28 | Fresno State | 1994 | 2000 | 2 | 2 | 0 | 0 | 1.000 | 77 | 20 | 57 | 38.5 | 10.0 | 28.5 | Game-by-Game |
| 29 | Georgia | 1992 | 1992 | 1 | 0 | 1 | 0 | .000 | 14 | 21 | -7 | 14.0 | 21.0 | -7.0 | Game-by-Game |
| 30 | Great Lakes Navy | 1943 | 1944 | 2 | 1 | 1 | 0 | .500 | 32 | 19 | 13 | 16.0 | 9.5 | 6.5 | Game-by-Game |
| 31 | Houston | 1994 | 1994 | 1 | 1 | 0 | 0 | 1.000 | 52 | 0 | 52 | 52.0 | 0.0 | 52.0 | Game-by-Game |
| 32 | Illinois | 1904 | 2012 | 98 | 65 | 30 | 3 | .679 | 2131 | 1265 | 866 | 21.7 | 12.9 | 8.8 | Game-by-Game |
| 33 | Indiana | 1904 | 2012 | 82 | 69 | 9 | 4 | .866 | 2170 | 846 | 1324 | 26.5 | 10.3 | 16.1 | Game-by-Game |
| 34 | Iowa | 1922 | 2010 | 63 | 46 | 14 | 3 | .754 | 1643 | 869 | 774 | 26.1 | 13.8 | 12.3 | Game-by-Game |
| 35 | Iowa Pre-Flight | 1942 | 1943 | 2 | 1 | 1 | 0 | .500 | 54 | 40 | 14 | 27.0 | 20.0 | 7.0 | Game-by-Game |
| 36 | Kansas State | 2003 | 2003 | 1 | 1 | 0 | 0 | 1.000 | 35 | 28 | 7 | 35.0 | 28.0 | 7.0 | Game-by-Game |
| 37 | Kent State | 2002 | 2007 | 2 | 2 | 0 | 0 | 1.000 | 99 | 20 | 79 | 49.5 | 10.0 | 39.5 | Game-by-Game |
| 38 | Kentucky | 1919 | 1935 | 2 | 2 | 0 | 0 | 1.000 | 68 | 6 | 62 | 34.0 | 3.0 | 31.0 | Game-by-Game |
| 39 | Louisiana State | 1987 | 2007 | 3 | 1 | 1 | 1 | .500 | 73 | 84 | -11 | 24.3 | 28.0 | -3.7 | Game-by-Game |
| 40 | Louisville | 1991 | 1992 | 2 | 2 | 0 | 0 | 1.000 | 43 | 34 | 9 | 21.5 | 17.0 | 4.5 | Game-by-Game |
| Record | Totals | Per Game | |||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 41 | Marshall | 2004 | 2010 | 2 | 2 | 0 | 0 | 1.000 | 69 | 28 | 41 | 34.5 | 14.0 | 20.5 | Game-by-Game |
| 42 | Miami (FL) | 1977 | 2011 | 5 | 3 | 2 | 0 | .600 | 95 | 95 | 0 | 19.0 | 19.0 | 0.0 | Game-by-Game |
| 43 | Miami (OH) | 2000 | 2012 | 3 | 3 | 0 | 0 | 1.000 | 117 | 40 | 77 | 39.0 | 13.3 | 25.7 | Game-by-Game |
| 44 | Michigan | 1904 | 2012 | 96 | 45 | 47 | 4 | .490 | 1475 | 1517 | -42 | 15.4 | 15.8 | -0.4 | Game-by-Game |
| 45 | Michigan State | 1951 | 2012 | 40 | 28 | 12 | 0 | .700 | 1008 | 615 | 393 | 25.2 | 15.4 | 9.8 | Game-by-Game |
| 46 | Minnesota | 1921 | 2010 | 50 | 43 | 7 | 0 | .860 | 1537 | 637 | 900 | 30.7 | 12.7 | 18.0 | Game-by-Game |
| 47 | Missouri | 1939 | 1998 | 12 | 10 | 1 | 1 | .875 | 328 | 126 | 202 | 27.3 | 10.5 | 16.8 | Game-by-Game |
| 48 | Navy | 1930 | 2009 | 4 | 4 | 0 | 0 | 1.000 | 109 | 55 | 54 | 27.3 | 13.8 | 13.5 | Game-by-Game |
| 49 | Nebraska | 1955 | 2012 | 4 | 3 | 1 | 0 | .750 | 152 | 99 | 53 | 38.0 | 24.8 | 13.3 | Game-by-Game |
| 50 | New Mexico State | 2009 | 2009 | 1 | 1 | 0 | 0 | 1.000 | 45 | 0 | 45 | 45.0 | 0.0 | 45.0 | Game-by-Game |
| 51 | New York University | 1936 | 1938 | 2 | 2 | 0 | 0 | 1.000 | 92 | 0 | 92 | 46.0 | 0.0 | 46.0 | Game-by-Game |
| 52 | North Carolina | 1962 | 1975 | 4 | 3 | 1 | 0 | .750 | 105 | 42 | 63 | 26.3 | 10.5 | 15.8 | Game-by-Game |
| 53 | North Carolina State | 2003 | 2004 | 2 | 2 | 0 | 0 | 1.000 | 66 | 52 | 14 | 33.0 | 26.0 | 7.0 | Game-by-Game |
| 54 | Northern Illinois | 2006 | 2006 | 1 | 1 | 0 | 0 | 1.000 | 35 | 12 | 23 | 35.0 | 12.0 | 23.0 | Game-by-Game |
| 55 | Northwestern | 1913 | 2008 | 74 | 59 | 14 | 1 | .804 | 2057 | 688 | 1369 | 27.8 | 9.3 | 18.5 | Game-by-Game |
| 56 | Notre Dame | 1935 | 2005 | 5 | 3 | 2 | 0 | .600 | 123 | 87 | 36 | 24.6 | 17.4 | 7.2 | Game-by-Game |
| 57 | Ohio | 1999 | 2010 | 3 | 3 | 0 | 0 | 1.000 | 109 | 37 | 72 | 36.3 | 12.3 | 24.0 | Game-by-Game |
| 58 | Oklahoma | 1977 | 1983 | 2 | 1 | 1 | 0 | .500 | 52 | 43 | 9 | 26.0 | 21.5 | 4.5 | Game-by-Game |
| 59 | Oklahoma State | 1989 | 2004 | 2 | 2 | 0 | 0 | 1.000 | 70 | 20 | 50 | 35.0 | 10.0 | 25.0 | Game-by-Game |
| 60 | Oregon | 1957 | 2009 | 8 | 8 | 0 | 0 | 1.000 | 190 | 69 | 121 | 23.8 | 8.6 | 15.1 | Game-by-Game |
| Record | Totals | Per Game | |||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 61 | Oregon State | 1974 | 1984 | 2 | 2 | 0 | 0 | 1.000 | 73 | 24 | 49 | 36.5 | 12.0 | 24.5 | Game-by-Game |
| 62 | Penn State | 1956 | 2012 | 27 | 15 | 12 | 0 | .556 | 549 | 463 | 86 | 20.3 | 17.1 | 3.2 | Game-by-Game |
| 63 | Pennsylvania | 1932 | 1953 | 3 | 3 | 0 | 0 | 1.000 | 51 | 13 | 38 | 17.0 | 4.3 | 12.7 | Game-by-Game |
| 64 | Pittsburgh | 1929 | 1996 | 25 | 19 | 5 | 1 | .780 | 678 | 290 | 388 | 27.1 | 11.6 | 15.5 | Game-by-Game |
| 65 | Princeton | 1927 | 1928 | 2 | 0 | 1 | 1 | .250 | 6 | 26 | -20 | 3.0 | 13.0 | -10.0 | Game-by-Game |
| 66 | Purdue | 1919 | 2012 | 55 | 39 | 14 | 2 | .727 | 1334 | 740 | 594 | 24.3 | 13.5 | 10.8 | Game-by-Game |
| 67 | Rice | 1993 | 1996 | 2 | 2 | 0 | 0 | 1.000 | 104 | 14 | 90 | 52.0 | 7.0 | 45.0 | Game-by-Game |
| 68 | San Diego State | 2001 | 2005 | 3 | 3 | 0 | 0 | 1.000 | 70 | 31 | 39 | 23.3 | 10.3 | 13.0 | Game-by-Game |
| 69 | San Jose State | 2002 | 2002 | 1 | 1 | 0 | 0 | 1.000 | 50 | 7 | 43 | 50.0 | 7.0 | 43.0 | Game-by-Game |
| 70 | South Carolina | 2000 | 2001 | 2 | 0 | 2 | 0 | .000 | 35 | 55 | -20 | 17.5 | 27.5 | -10.0 | Game-by-Game |
| 71 | Southern California | 1937 | 2009 | 23 | 9 | 13 | 1 | .413 | 377 | 404 | -27 | 16.4 | 17.6 | -1.2 | Game-by-Game |
| 72 | Southern Methodist | 1950 | 1978 | 9 | 7 | 1 | 1 | .833 | 241 | 125 | 116 | 26.8 | 13.9 | 12.9 | Game-by-Game |
| 73 | Stanford | 1955 | 1982 | 5 | 2 | 3 | 0 | .400 | 93 | 95 | -2 | 18.6 | 19.0 | -0.4 | Game-by-Game |
| 74 | Syracuse | 1979 | 1992 | 5 | 4 | 1 | 0 | .800 | 140 | 74 | 66 | 28.0 | 14.8 | 13.2 | Game-by-Game |
| 75 | Tennessee | 1995 | 1995 | 1 | 0 | 1 | 0 | .000 | 14 | 20 | -6 | 14.0 | 20.0 | -6.0 | Game-by-Game |
| 76 | Texas | 2005 | 2008 | 3 | 1 | 2 | 0 | .333 | 67 | 56 | 11 | 22.3 | 18.7 | 3.7 | Game-by-Game |
| 77 | Texas A&M | 1963 | 1998 | 4 | 4 | 0 | 0 | 1.000 | 125 | 39 | 86 | 31.3 | 9.8 | 21.5 | Game-by-Game |
| 78 | Texas Christian | 1937 | 1973 | 6 | 4 | 1 | 1 | .750 | 148 | 35 | 113 | 24.7 | 5.8 | 18.8 | Game-by-Game |
| 79 | Texas Tech | 1990 | 2002 | 2 | 2 | 0 | 0 | 1.000 | 62 | 31 | 31 | 31.0 | 15.5 | 15.5 | Game-by-Game |
| 80 | Toledo | 1998 | 2011 | 3 | 3 | 0 | 0 | 1.000 | 114 | 22 | 92 | 38.0 | 7.3 | 30.7 | Game-by-Game |
| Record | Totals | Per Game | |||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff | Notes |
| 81 | Troy | 2008 | 2008 | 1 | 1 | 0 | 0 | 1.000 | 28 | 10 | 18 | 28.0 | 10.0 | 18.0 | Game-by-Game |
| 82 | UCLA | 1961 | 2001 | 9 | 4 | 4 | 1 | .500 | 146 | 128 | 18 | 16.2 | 14.2 | 2.0 | Game-by-Game |
| 83 | Utah | 1986 | 1986 | 1 | 1 | 0 | 0 | 1.000 | 64 | 6 | 58 | 64.0 | 6.0 | 58.0 | Game-by-Game |
| 84 | Vanderbilt | 1931 | 1933 | 2 | 1 | 1 | 0 | .500 | 41 | 26 | 15 | 20.5 | 13.0 | 7.5 | Game-by-Game |
| 85 | Virginia | 1933 | 1933 | 1 | 1 | 0 | 0 | 1.000 | 75 | 0 | 75 | 75.0 | 0.0 | 75.0 | Game-by-Game |
| 86 | Washington | 1957 | 2007 | 11 | 8 | 3 | 0 | .727 | 268 | 207 | 61 | 24.4 | 18.8 | 5.5 | Game-by-Game |
| 87 | Washington State | 1952 | 2002 | 8 | 8 | 0 | 0 | 1.000 | 299 | 104 | 195 | 37.4 | 13.0 | 24.4 | Game-by-Game |
| 88 | West Virginia | 1987 | 1998 | 2 | 2 | 0 | 0 | 1.000 | 58 | 20 | 38 | 29.0 | 10.0 | 19.0 | Game-by-Game |
| 89 | Wisconsin | 1913 | 2012 | 78 | 55 | 18 | 5 | .737 | 1735 | 984 | 751 | 22.2 | 12.6 | 9.6 | Game-by-Game |
| 90 | Wyoming | 1997 | 1997 | 1 | 1 | 0 | 0 | 1.000 | 24 | 10 | 14 | 24.0 | 10.0 | 14.0 | Game-by-Game |