12 Games
| G | Date | Day | School | Opponent | Conf | Pts | Opp | W | L | Streak | Notes | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sep 4, 2010 | Sat | Colorado | N | Colorado State | MWC | W | 24 | 3 | 1 | 0 | W 1 | |
| 2 | Sep 11, 2010 | Sat | Colorado | @ | California | Pac-10 | L | 7 | 52 | 1 | 1 | L 1 | |
| 3 | Sep 18, 2010 | Sat | Colorado | Hawaii | WAC | W | 31 | 13 | 2 | 1 | W 1 | ||
| 4 | Oct 2, 2010 | Sat | Colorado | Georgia | SEC | W | 29 | 27 | 3 | 1 | W 2 | ||
| 5 | Oct 9, 2010 | Sat | Colorado | @ | (24) Missouri | Big 12 | L | 0 | 26 | 3 | 2 | L 1 | |
| 6 | Oct 16, 2010 | Sat | Colorado | Baylor | Big 12 | L | 25 | 31 | 3 | 3 | L 2 | ||
| 7 | Oct 23, 2010 | Sat | Colorado | Texas Tech | Big 12 | L | 24 | 27 | 3 | 4 | L 3 | ||
| 8 | Oct 30, 2010 | Sat | Colorado | @ | (11) Oklahoma | Big 12 | L | 10 | 43 | 3 | 5 | L 4 | |
| 9 | Nov 6, 2010 | Sat | Colorado | @ | Kansas | Big 12 | L | 45 | 52 | 3 | 6 | L 5 | |
| 10 | Nov 13, 2010 | Sat | Colorado | Iowa State | Big 12 | W | 34 | 14 | 4 | 6 | W 1 | ||
| 11 | Nov 20, 2010 | Sat | Colorado | Kansas State | Big 12 | W | 44 | 36 | 5 | 6 | W 2 | ||
| 12 | Nov 26, 2010 | Fri | Colorado | @ | (16) Nebraska | Big 12 | L | 17 | 45 | 5 | 7 | L 1 |
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